Inverse Association between Cheese Consumption and Lower Cognitive Function in Japanese Community-Dwelling Older Adults Based on a Cross-Sectional Study

Author:

Kim Hunkyung1ORCID,Osuka Yosuke2,Kojima Narumi3,Sasai Hiroyuki3ORCID,Nakamura Kentaro4ORCID,Oba Chisato4,Sasaki Mayuki4,Suzuki Takao5

Affiliation:

1. Gaon Research Center, 402 Pangyo Medical Tower, Seongnam-shi 13466, Republic of Korea

2. Department of Frailty Research, Center for Gerontology and Social Science, Research Institute, National Center for Geriatrics and Gerontology, Obu 474-8511, Aichi, Japan

3. Research Team for Promoting Independence and Mental Health, Tokyo Metropolitan Institute of Gerontology, Itabashi 173-0015, Tokyo, Japan

4. Nutrition and Food Function Research Department, R&D Division, Meiji Co. Ltd., Hachioji 192-0919, Tokyo, Japan

5. Institute of Gerontology, J. F. Oberlin University, Machida 194-0294, Tokyo, Japan

Abstract

Diet modification may contribute to the prevention of age-related cognitive decline. The association between dairy product consumption and cognitive function in older people remains unknown. We investigated whether cheese intake is associated with lower cognitive function (LCF) in community-dwelling older adults. This cross-sectional study included 1503 adults aged over 65 years. The analyzed data were obtained through face-to-face interviews and functional ability measurement. Cognitive function was assessed using the mini-mental state examination (MMSE), and a score ≤23 was defined as LCF. The prevalence of LCF was 4.6%, and this group had smaller calf circumference, slower usual walking speed, and a more frequent history of anemia than subjects with MMSE scores >23. After adjusting for confounding factors, logistic regression analysis revealed cheese intake (odds ratio (OR) = 0.404, 95% confidence interval (CI) = 0.198–0.824), age (OR = 1.170, 95% CI = 1.089–1.256), usual walking speed (OR = 0.171, 95% CI = 0.062–0.472) and calf circumference (OR = 0.823, 95% CI = 0.747–0.908) to be significant factors associated with LCF. Although the present study was an analysis of cross-sectional data of Japanese community-dwelling older adults, the results suggest that cheese intake is inversely associated with LCF.

Funder

Grants-in-Aid for Scientific Research

Japan Agency for Medical Research and Development

Joint Research Grant

National Center for Geriatrics and Gerontology, and Meiji Co., Ltd.

Publisher

MDPI AG

Subject

Food Science,Nutrition and Dietetics

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