Development of a New Lightweight Multi-Channel Micro-Pipette Device

Abstract

In this study, to improve the efficiency of the pipetting workstation and reduce the impact of the pipetting device on the stability performance of the workstation, a novel fully automatic pipetting method is proposed. Based on this method, a lightweight, multifunctional, and quantitative twelve-channel pipetting device was designed. This device can achieve simultaneous quantitative liquid absorption for twelve channels and sequential interval liquid discharge for each channel. Initially, the overall functional requirements were determined, and with the aim of a lightweight design, the total weight of the device was controlled to be within 580 g through a reasonable structural design, material selection, and choice of driving source. The device’s overall dimensions are 170 mm × 70 mm × 180 mm (length × width × height), with a micropipetting volume ranging between 1.3 μL and 1.4 μL. Subsequently, factors affecting liquid suction stability were experimentally analyzed, and appropriate pipetting parameters were selected. The stability performance of this pipetting method during prolonged operation was investigated. Finally, the twelve-channel pipetting device was validated through experiments, demonstrating results that meet the national standards for the stability of a pipetting device. In summary, the device designed in this study exhibits novel design features, low cost, and modularity, thus demonstrating promising potential for applications in high-speed micro-volume pipetting.