Abstract
In this paper a novel control strategy is introduced in order to create optimal dosage profiles for individualized cancer treatment. This approach uses Nonlinear Model Predictive Control to construct optimal dosage protocols in conjunction with Robust Fixed Point Transformations which hinders the negative effect of inherent model uncertainties and measurement disturbances. The results are validated by extensive simulation on the proposed control algorithm from which conclusions were drawn.
Funder
H2020 European Research Council
Subject
Electrical and Electronic Engineering,Industrial and Manufacturing Engineering,Control and Optimization,Mechanical Engineering,Computer Science (miscellaneous),Control and Systems Engineering
Reference22 articles.
1. A robust fixed point transformation-based approach for type 1 diabetes control
2. European cancer mortality predictions for the year 2016 with focus on leukaemias
3. Tumor development under angiogenic signaling: A dynamical theory of tumor growth, treatment response, and postvascular dormancy;Hanhfeldt;Cancer Res.,1999
Cited by
7 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献