1. Critical Care and Perioperative Medicine Research Group, William Harvey Research Institute, Queen Mary University of London, London E1 4NS, UK
2. Department of Medicine, Faculty of Medicine, Imperial College London, London SW7 2AZ, UK
3. Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London E1 4NS, UK
4. Department of Medicine, Kings College London, London SE5 9RS, UK
5. St. George’s University of London, London SW17 0RE, UK
6. Molecular and Clinical Sciences Research Institute, St. George’s University of London, London SW17 0RE, UK