Affiliation:
1. Department of Veterinary Medicine, University of Perugia, Via San Costanzo 4, 06126 Perugia, Italy
2. CeRiDA (Research Center on Animal Pain), Department of Veterinary Medicine, University of Perugia, Via San Costanzo 4, 06126 Perugia, Italy
Abstract
The aim of this study was to compare three different anesthetic protocols administered intramuscularly (IM) in cats undergoing elective ovariectomy, while evaluating the quality of sedation, antinociceptive, isoflurane-sparing effect, and analgesia in the intra-operative and post-operative phases. A total of 71 female cats were sedated IM with alfaxalone (3 mg/kg) combined with either butorphanol (0.3 mg/kg), methadone (0.3 mg/kg), or pethidine (5 mg/kg). During surgery, vital parameters were constantly monitored; at the end of the procedure, the quality of recovery was assessed through a specific form and each cat was scored for perceived pain using the UNESP-Botucatu scale for 5 days, and rescue analgesia was provided with buprenorphine IM when indicated. Moreover, differences between two different post-operative resting regimens (hospital kennels vs. home) were also assessed. A significant difference emerged for the amount of IM dexmedetomidine required to achieve an adequate level of sedation for intravenous catheterization, highlighting a greater need in the pethidine group (p = 0.021). There was no significant difference between opioid groups for the requirement of intra-operative rescue analgesia, and the clinical parameters were kept within physiological ranges regardless of the opioid used in premedication. Lastly, differences between the UNESP-Botucatu scores were detected from day 3 to day 5 post-operatively, with lower scores in cats with home resting regimens compared to the hospitalized animals, likely due to the presence of an unfamiliar condition and the absence of a cat-friendly environment.
Reference44 articles.
1. Commentary ovariohysterectomy versus ovariectomy for elective sterilization of female dogs and cats: Is removal of the uterus necessary?;DeTora;J. Am. Vet. Med. Assoc.,2011
2. Pereira, M.A.A., Gonçalves, L.A., Evangelista, M.C., Thurler, R.S., Campos, K.D., Formenton, M.R., Patricio, G.C.F., Matera, J.M., Ambrósio, A.M., and Fantoni, D.T. (2018). Postoperative pain and short-term complications after two elective sterilization techniques: Ovariohysterectomy or ovariectomy in cats. BMC Vet. Res., 14.
3. Multicenter, randomized controlled trial of pain-related behaviors following routine neutering in dogs;Wagner;J. Am. Vet. Med. Assoc.,2008
4. A dog model to study ovary, ovarian ligament and visceral pain;Boscan;Vet. Anaesth. Analg.,2011
5. Ovariohysterectomy requires more post-operative analgesia than orchiectomy in dogs and cats;Quarterone;Can. Vet. J.,2017