Enzymatic Synthesis of 2-Chloropurine Arabinonucleosides with Chiral Amino Acid Amides at the C6 Position and an Evaluation of Antiproliferative Activity In Vitro
Author:
Affiliation:
1. Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya St. 16/10, 117997 Moscow, Russia
2. State N.N. Blokhin Russian Cancer Research Center, Kashirsky Highway, 24, 115478 Moscow, Russia
Abstract
Funder
Russian Science Foundation
Publisher
MDPI AG
Subject
Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Computer Science Applications,Spectroscopy,Molecular Biology,General Medicine,Catalysis
Link
https://www.mdpi.com/1422-0067/24/7/6223/pdf
Reference47 articles.
1. A Structure–Activity Relationship Study of Bitopic N6-Substituted Adenosine Derivatives as Biased Adenosine A1 Receptor Agonists;Aurelio;J. Med. Chem.,2018
2. John daly lecture: Structure-guided drug design for adenosine and P2Y receptors;Jacobson;Comput. Struct. Biotechnol. J.,2015
3. The A3 adenosine receptor is highly expressed in tumor versus normal cells: Potential target for tumor growth inhibition;Madi;Clin. Cancer Res.,2004
4. Adenosine receptors in colon carcinoma tissues and colon tumoral cell lines: Focus on the A3 adenosine subtype;Gessi;J. Cell. Physiol.,2007
5. Some short-chain N6-substituted adenosine analogs with antitumor properties;Fleysher;J. Med. Chem.,1980
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