N-Type Ca Channel in Epileptic Syndromes and Epilepsy: A Systematic Review of Its Genetic Variants-Reference-Cited by-同舟云学术

N-Type Ca Channel in Epileptic Syndromes and Epilepsy: A Systematic Review of Its Genetic Variants

Published:2023-03-23 Issue:7 Volume:24 Page:6100
ISSN:1422-0067
Container-title:International Journal of Molecular Sciences
language:en
Short-container-title:IJMS

Author:

Mayo Sonia¹²^ORCID,Gómez-Manjón Irene¹²^ORCID,Marco-Hernández Ana Victoria³⁴,Fernández-Martínez Francisco Javier¹²^ORCID,Camacho Ana⁵,Martínez Francisco⁴⁶⁷^ORCID

Affiliation:

1. Genetics and Inheritance Research Group, Instituto de Investigación Sanitaria Hospital 12 de Octubre, 28041 Madrid, Spain

2. Department of Genetics, Hospital Universitario 12 de Octubre, 28041 Madrid, Spain

3. Neuropediatric Unit, Hospital Universitario Doctor Peset, 46017 Valencia, Spain

4. Translational Research in Genetics, Instituto de Investigación Sanitaria La Fe, 46026 Valencia, Spain

5. Division of Pediatric Neurology, Department of Neurology, Hospital Universitario 12 de Octubre, Universidad Complutense de Madrid, 28040 Madrid, Spain

6. Genomic Unit, Instituto de Investigación Sanitaria La Fe, 46026 Valencia, Spain

7. Genetics Unit, Hospital Universitario y Politecnico La Fe, 46026 Valencia, Spain

Abstract

N-type voltage-gated calcium channel controls the release of neurotransmitters from neurons. The association of other voltage-gated calcium channels with epilepsy is well-known. The association of N-type voltage-gated calcium channels and pain has also been established. However, the relationship between this type of calcium channel and epilepsy has not been specifically reviewed. Therefore, the present review systematically summarizes existing publications regarding the genetic associations between N-type voltage-dependent calcium channel and epilepsy.

Funder

Mutua Madrileña Foundation

Publisher

MDPI AG

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Computer Science Applications,Spectroscopy,Molecular Biology,General Medicine,Catalysis

Link

https://www.mdpi.com/1422-0067/24/7/6100/pdf

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