Synthesis and Wittig Rearrangement of 3- and 4-Benzyloxyphenylphosphonamidates-Reference-Cited by-同舟云学术

Synthesis and Wittig Rearrangement of 3- and 4-Benzyloxyphenylphosphonamidates

Published:2023-02-03 Issue:1 Volume:4 Page:59-69
ISSN:2673-401X
Container-title:Organics
language:en
Short-container-title:Organics

Author:

Aitken R. Alan¹^ORCID,Inwood Ryan A.¹

Affiliation:

1. EaStCHEM School of Chemistry, University of St Andrews, North Haugh, St Andrews, Fife KY16 9ST, UK

Abstract

A series of seven O-ethyl-N-butylphenylphosphonamidates with benzyl ether substituents at the para or meta position have been prepared and fully characterised. Upon treatment with n-butyllithium in THF at RT, these undergo Wittig rearrangement in six cases to give the novel phosphonamidate-substituted diarylmethanols in moderate to good yield.

Funder

EPSRC(UK) and CRITICAT Centre

Publisher

MDPI AG

Subject

Industrial and Manufacturing Engineering

Link

https://www.mdpi.com/2673-401X/4/1/5/pdf

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1. Synthesis and Butyllithium-Induced Cyclisation of 2-Benzyloxyphenylphosphonamidates Giving 2,3-Dihydrobenzo[d][1,3]oxaphospholes;Organics;2024-02-01

2. A tribute to Professor Aitken;Arkivoc;2023-11-17