Abstract
The occurrence of diseases is usually accompanied by changes in protein levels and types. These differentially expressed proteins can be used as biomarkers for the diagnosis and treatment of diseases. In recent years, luminescent iridium(III) complexes have attracted much attention in the field of protein-based disease diagnosis due to their excellent optical properties. In particular, affinity-based luminescent iridium(III) complexes have the advantage of evaluating protein information with minimal interference on their biological activities. In this review, we summarize the current advances in affinity-based luminescent iridium(III) complexes for the detection of disease-related proteins. Moreover, the future perspective for affinity-based iridium(III) complexes is discussed.
Funder
Natural Science Basic Research Program of Shaanxi
Natural Science Foundation of Chongqing, China
National Natural Science Foundation of China
Fundamental Research Funds for the Central Universities
Shanghai Sailing Program
Guangdong Basic and Applied Basic Research Foundation
Hainan Province Science and Technology Special Fund
Science and Technology Development Fund, Macau SAR
University of Macau
Cited by
1 articles.
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