Abstract
In recent decades, microfluidics have significantly advanced nerve regeneration research. Microfluidic devices can provide an accurate simulation of in vivo microenvironment for different research purposes such as analyzing myelin growth inhibitory factors, screening drugs, assessing nerve growth factors, and exploring mechanisms of neural injury and regeneration. The microfluidic platform offers technical supports for nerve regeneration that enable precise spatio-temporal control of cells, such as neuron isolation, single-cell manipulation, neural patterning, and axon guidance. In this paper, we review the development and recent advances of microfluidic platforms for nerve regeneration research.
Funder
National Key R&D Program of China
National Natural Science Foundation of China
Subject
Fluid Flow and Transfer Processes,Computer Science Applications,Process Chemistry and Technology,General Engineering,Instrumentation,General Materials Science
Reference85 articles.
1. https://www.spinalcord.com/blog/complete-vs.-incomplete-spinal-cord-injuries
2. Clinical diagnosis and prognosis following spinal cord injury;Burns;Handb. Clin. Neurol.,2012
3. Microfluidic platforms for the study of neuronal injury in vitro
4. Integrated Microfluidics Platforms for Investigating Injury and Regeneration of CNS Axons
5. Over a century of neuron culture: From the hanging drop to microfluidic devices;Millet;Yale J. Biol. Med.,2012
Cited by
5 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献