Dietary Intake and Oral Glucose Tolerance Test Results in Women with Gestational Diabetes

Author:

das Chagas Lucas Almeida1ORCID,Torloni Maria Regina12ORCID,Silva-Neto Luiz Gonzaga Ribeiro3ORCID,Dualib Patricia Medici4ORCID,de Sousa Rosângela Maria Lopes5ORCID,Bittencourt Jalila Andréa Sampaio6ORCID,Araujo Júnior Edward1ORCID,Granese Roberta7ORCID,Mattar Rosiane1ORCID

Affiliation:

1. Department of Obstetrics, Paulista School of Medicine, Federal University of São Paulo (EPM-UNIFESP), São Paulo 04023-062, SP, Brazil

2. Evidence Based Health Care, Department of Medicine, Paulista School of Medicine, Federal University of São Paulo (EPM-UNIFESP), São Paulo 04023-900, SP, Brazil

3. Department of Nutrition, Paulista School of Medicine, Federal University of São Paulo (EPM-UNIFESP), São Paulo 04023-062, SP, Brazil

4. Discipline of Endocrinology, Department of Medicine, Paulista School of Medicine, Federal University of São Paulo (EPM-UNIFESP), São Paulo 04038-001, SP, Brazil

5. Department of Nutrition, CEUMA University, São Luiz 65075-120, MA, Brazil

6. Laboratory of Biological Information Processing, Department of Electrical Engineering, Federal University of Maranhão (UFMA), São Luiz 65080-805, MA, Brazil

7. Department of Biomedical and Dental Sciences and Morphofunctional Imaging, “G. Martino” University Hospital, 98100 Messina, Italy

Abstract

Background/Objective: Diet is a risk factor for gestational diabetes mellitus (GDM). There are few studies on women’s diet and glucose tolerance test (GTT) results during pregnancy. The objective of this study was to evaluate the relationship between one’s previous diet and the number of abnormal values on the diagnostic GTT in women with GDM. We hypothesized that there would be an inverse relation between antioxidant micronutrient consumption and the number of abnormal GTT values. Methods: This cross-sectional study included 60 women diagnosed with GDM (2-h, 75 g-GTT), divided in two groups as follows: 1 abnormal glucose value and 2–3 abnormal values. Shortly after the diagnosis, participants answered a validated food frequency questionnaire to assess their food consumption in the last 6 months. The Mann–Whitney test was used to compare the dietary intake of the participants in the two groups. Results: The participant characteristics were similar. The median intake of total calories, carbohydrates, lipids, and proteins did not differ significantly between groups. Participants with 1 abnormal GTT value had significantly higher intakes of fiber (11.9 vs. 11.0 g/day p = 0.049), vitamin D (40.6 vs. 40.4 mcg/day p = 0.049), and vitamin C (180.0 vs. 151.0 mg/day p = 0.008) than those with 2–3 abnormal values. Conclusions: Our results suggest a possible association between the consumption of fiber and antioxidant micronutrients and the number of abnormal GTT values.

Publisher

MDPI AG

Reference62 articles.

1. World Health Organization (2014). Diagnostic Criteria and Classification of Hyperglycaemia First Detected in Pregnancy: A World Health Organization Guideline. Diabetes Res. Clin. Pract., 103, 341–363.

2. A Clinical Update on Gestational Diabetes Mellitus;Sweeting;Endocr. Rev.,2022

3. Magliano, D.J., Boyko, E.J., and IDF Diabetes Atlas 10th Edition Scientific Committee (2021). IDF Diabetes Atlas, International Diabetes Federation. [10th ed.].

4. Global Estimates of the Prevalence of Hyperglycaemia in Pregnancy;Guariguata;Diabetes Res. Clin. Pract.,2014

5. Impact of the International Association of Diabetes and Pregnancy Study Groups Criteria for Gestational Diabetes;Trujillo;Diabetes Res. Clin. Pract.,2015

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