In Situ Measurement Method Based on Edge Detection and Superpixel for Crystallization Imaging at High-Solid Concentrations

Abstract

To facilitate measuring crystal sizes during batch crystallization at high-solid concentrations by using an invasive imaging system, an in situ imaging measurement strategy based on edge detection and superpixel is proposed for the ambiguous boundary problem of large amounts of crystals. Firstly, an image filtering is employed to cope with image degradation caused by noise disturbance and suspension turbulence in the crystallizer. Subsequently, an image segmentation method is developed by utilizing improved edge detection and superpixel, which can be easily performed for crystal extraction. Accordingly, crystal size measurement can be developed for evaluation of the crystal size distribution. The experiment results on α-form L-glutamic acid present the effectiveness of the proposed method.