Brain Waste Removal System and Sleep: Photobiomodulation as an Innovative Strategy for Night Therapy of Brain Diseases-Reference-Cited by-同舟云学术

Brain Waste Removal System and Sleep: Photobiomodulation as an Innovative Strategy for Night Therapy of Brain Diseases

Published:2023-02-06 Issue:4 Volume:24 Page:3221
ISSN:1422-0067
Container-title:International Journal of Molecular Sciences
language:en
Short-container-title:IJMS

Author:

Semyachkina-Glushkovskaya Oxana¹²,Fedosov Ivan²,Penzel Thomas²³^ORCID,Li Dongyu⁴⁵,Yu Tingting⁴⁶,Telnova Valeria²,Kaybeleva Elmira²,Saranceva Elena²,Terskov Andrey²,Khorovodov Alexander²,Blokhina Inna²^ORCID,Kurths Jürgen¹²⁷,Zhu Dan⁴⁶

Affiliation:

1. Institute of Physics, Humboldt University, Newtonstrasse 15, 12489 Berlin, Germany

2. Department of Biology, Saratov State University, Astrakhanskaya 82, 410012 Saratov, Russia

3. Sleep Medicine Center, Charité-Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany

4. Optics Valley Laboratory, Huazhong University of Science and Technology, Wuhan 430074, China

5. Advanced Biomedical Imaging Facility, School of Optical Electronic Information, Huazhong University of Science and Technology, Wuhan 430074, China

6. Britton Chance Center for Biomedical Photonics, MoE Key Laboratory for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, Advanced Biomedical Imaging Facility, Huazhong University of Science and Technology, Wuhan 430074, China

7. Potsdam Institute for Climate Impact Research, Department of Complexity Science, Telegrafenberg A31, 14473 Potsdam, Germany

Abstract

Emerging evidence suggests that an important function of the sleeping brain is the removal of wastes and toxins from the central nervous system (CNS) due to the activation of the brain waste removal system (BWRS). The meningeal lymphatic vessels (MLVs) are an important part of the BWRS. A decrease in MLV function is associated with Alzheimer’s and Parkinson’s diseases, intracranial hemorrhages, brain tumors and trauma. Since the BWRS is activated during sleep, a new idea is now being actively discussed in the scientific community: night stimulation of the BWRS might be an innovative and promising strategy for neurorehabilitation medicine. This review highlights new trends in photobiomodulation of the BWRS/MLVs during deep sleep as a breakthrough technology for the effective removal of wastes and unnecessary compounds from the brain in order to increase the neuroprotection of the CNS as well as to prevent or delay various brain diseases.

Funder

RF Governmental

RSF

RFBR

Innovation Fund of WNLO and Innovation Project of Optics Valley Laboratory

National Natural Science Foundation of China

Publisher

MDPI AG

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Computer Science Applications,Spectroscopy,Molecular Biology,General Medicine,Catalysis

Link

https://www.mdpi.com/1422-0067/24/4/3221/pdf

Reference177 articles.

1. The inescapable drive to sleep: Overlapping mechanisms of sleep and sedation;Franks;Science,2021

2. Association of sleep duration in middle and old age with incidence of dementia;Sabia;Nat. Commun.,2021

3. Effect of 1 night of total sleep deprivation on cerebrospinal fluid β-amyloid 42 in healthy middle-aged men: A randomized clinical trial;Ooms;JAMA Neurol.,2014

4. β-Amyloid accumulation in the human brain after one night of sleep deprivation;Wanga;Proc. Natl. Acad. Sci. USA,2018

5. Reduced non–rapid eye movement sleep is associated with tau pathology in early Alzheimer’s disease;Lucey;Sci. Transl. Med.,2019

Cited by 13 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Natural Compounds for Preventing Age-Related Diseases and Cancers;International Journal of Molecular Sciences;2024-07-09

2. Promising Strategies to Reduce the SARS-CoV-2 Amyloid Deposition in the Brain and Prevent COVID-19-Exacerbated Dementia and Alzheimer’s Disease;Pharmaceuticals;2024-06-16

3. Editorial on the special issue on neuro-sleep as a complex system;The European Physical Journal Special Topics;2024-04-23

4. Efficacy of biologically-directed daylight therapy on sleep and circadian rhythm in Parkinson's disease: a randomised, double-blind, parallel-group, active-controlled, phase 2 clinical trial;eClinicalMedicine;2024-03

5. Method for real-time optical brain monitoring in freely moving mice during wakefulness and natural sleep;The European Physical Journal Special Topics;2024-02-22