Engineering Materials and Devices for the Prevention, Diagnosis, and Treatment of COVID-19 and Infectious Diseases-Reference-Cited by-同舟云学术

Engineering Materials and Devices for the Prevention, Diagnosis, and Treatment of COVID-19 and Infectious Diseases

Published:2023-08-30 Issue:17 Volume:13 Page:2455
ISSN:2079-4991
Container-title:Nanomaterials
language:en
Short-container-title:Nanomaterials

Author:

Soto Jennifer¹,Linsley Chase¹^ORCID,Song Yang¹,Chen Binru¹,Fang Jun¹²,Neyyan Josephine¹,Davila Raul¹,Lee Brandon¹^ORCID,Wu Benjamin¹³,Li Song¹⁴⁵⁶^ORCID

Affiliation:

1. Department of Bioengineering, University of California Los Angeles, Los Angeles, CA 90095, USA

2. School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai 200240, China

3. Department of Dentistry, University of California Los Angeles, Los Angeles, CA 90095, USA

4. Department of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA

5. Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California Los Angeles, Los Angeles, CA 90095, USA

6. Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA

Abstract

Following the global spread of COVID-19, scientists and engineers have adapted technologies and developed new tools to aid in the fight against COVID-19. This review discusses various approaches to engineering biomaterials, devices, and therapeutics, especially at micro and nano levels, for the prevention, diagnosis, and treatment of infectious diseases, such as COVID-19, serving as a resource for scientists to identify specific tools that can be applicable for infectious-disease-related research, technology development, and treatment. From the design and production of equipment critical to first responders and patients using three-dimensional (3D) printing technology to point-of-care devices for rapid diagnosis, these technologies and tools have been essential to address current global needs for the prevention and detection of diseases. Moreover, advancements in organ-on-a-chip platforms provide a valuable platform to not only study infections and disease development in humans but also allow for the screening of more effective therapeutics. In addition, vaccines, the repurposing of approved drugs, biomaterials, drug delivery, and cell therapy are promising approaches for the prevention and treatment of infectious diseases. Following a comprehensive review of all these topics, we discuss unsolved problems and future directions.

Funder

National Institute of Health

California Institute for Regenerative Medicine

UCLA David Geffen School of Medicine—Oversight COVID-19 Research Committee

Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research Award Program

Publisher

MDPI AG

Subject

General Materials Science,General Chemical Engineering

Link

https://www.mdpi.com/2079-4991/13/17/2455/pdf

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