Hydrogel Wound Dressings Accelerating Healing Process of Wounds in Movable Parts

Author:

Yu Pengcheng1,Wei Liqi2,Yang Zhiqi1,Liu Xin2,Ma Hongxia2ORCID,Zhao Jian1,Liu Lulu1,Wang Lili1,Chen Rui1,Cheng Yan2ORCID

Affiliation:

1. Jilin Provincial Key Laboratory of Human Health Status Identification and Function Enhancement, School of Materials Science and Engineering, Changchun University, Changchun 130022, China

2. Center of the Chinese Ministry of Education for Bioreactor and Pharmaceutical Development, College of Life Science, Engineering Research, Jilin Agricultural University, Changchun 130118, China

Abstract

Skin is the largest organ in the human body and requires proper dressing to facilitate healing after an injury. Wounds on movable parts, such as the elbow, knee, wrist, and neck, usually undergo delayed and inefficient healing due to frequent movements. To better accommodate movable wounds, a variety of functional hydrogels have been successfully developed and used as flexible wound dressings. On the one hand, the mechanical properties, such as adhesion, stretchability, and self-healing, make these hydrogels suitable for mobile wounds and promote the healing process; on the other hand, the bioactivities, such as antibacterial and antioxidant performance, could further accelerate the wound healing process. In this review, we focus on the recent advances in hydrogel-based movable wound dressings and propose the challenges and perspectives of such dressings.

Funder

National Natural Science Foundation of China

Science and Technology Development Project Foundation of Jilin Province

Program of Jilin Provincial Development and Reform Commission

Scientific and Technological Project of Jilin Provincial Department of Education

Changchun University

Publisher

MDPI AG

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