(±)-N-(1,2-Bis(3,4-dimethoxyphenyl)ethyl)-2-(2-fluoro-[1,1′-biphenyl]-4-yl)propanamide-Reference-Cited by-同舟云学术

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(±)-N-(1,2-Bis(3,4-dimethoxyphenyl)ethyl)-2-(2-fluoro-[1,1′-biphenyl]-4-yl)propanamide

Published:2023-06-30 Issue:3 Volume:2023 Page:M1679
ISSN:1422-8599
Container-title:Molbank
language:en
Short-container-title:Molbank

Author:

Manolov Stanimir¹^ORCID,Bojilov Dimitar¹^ORCID,Ivanov Iliyan¹^ORCID,Nedialkov Paraskev²^ORCID

Affiliation:

1. Department of Organic Chemistry, Faculty of Chemistry, University of Plovdiv, 24 Tsar Assen Str., 4000 Plovdiv, Bulgaria

2. Department of Pharmacognosy, Faculty of Pharmacy, Medical University of Sofia, 2 Dunav Str., 1000 Sofia, Bulgaria

Abstract

The title compound, (±)-N-(1,2-bis(3,4-dimethoxyphenyl)ethyl)-2-(2-fluoro-[1,1′-biphenyl]-4-yl)propanamide, was obtained for the first time from 1,2-bis(3,4-dimethoxyphenyl) ethan-1-amine and (±)-flurbiprofen in one step. The newly synthesized bio-functional hybrid compound was fully characterized using 1H, 13C-NMR, UV, and mass spectral data.

Funder

University of Plovdiv

Publisher

MDPI AG

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://www.mdpi.com/1422-8599/2023/3/M1679/pdf

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3. Gözler, B. (1987). Pavine and Isopavine Alkaloids, Academic Press, Inc.

4. General and catalytic enantioselective approach to isopavine alkaloids;Sun;J. Org. Chem.,2017

5. Concise enantioselective total synthesis of isopavine alkaloids;Pu;J. Org. Chem.,2023

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