The Great Game between Plants and Viruses: A Focus on Protein Homeostasis
-
Published:2023-08-09
Issue:16
Volume:24
Page:12582
-
ISSN:1422-0067
-
Container-title:International Journal of Molecular Sciences
-
language:en
-
Short-container-title:IJMS
Author:
Sun Hangjun12,
Jing Xinxin12,
Wang Chaonan12,
Wang Pengyue12,
Huang Ziting12,
Sun Bingjian12,
Li Pengbai12,
Li Honglian12,
Zhang Chao12ORCID
Affiliation:
1. The Engineering Research Center for Plant Health Protection Technology in Henan Province, Henan Agricultural University, Zhengzhou 450002, China
2. Department of Plant Pathology, College of Plant Protection, Henan Agricultural University, Zhengzhou 450002, China
Abstract
Plant viruses are tiny pathogenic obligate parasites that cause significant damage to global crop production. They exploit and manipulate the cellular components of host plants to ensure their own survival. In response, plants activate multiple defense signaling pathways, such as gene silencing and plant hormone signaling, to hinder virus propagation. Growing evidence suggests that the regulation of protein homeostasis plays a vital role in the ongoing battle between plants and viruses. The ubiquitin-proteasome-degradation system (UPS) and autophagy, as two major protein-degradation pathways, are widely utilized by plants and viruses in their arms race. One the one hand, these pathways act as essential components of plant’s antiviral defense system by facilitating the degradation of viral proteins; on the other hand, viruses exploit the UPS and autophagy to create a favorable intracellular environment for viral infection. This review aims to provide a comprehensive summary of the events involved in protein homeostasis regulation during viral infection in plants. Gaining knowledge in this area will enhance our understanding of the complex interplay between plants and viruses.
Funder
China Postdoctoral Science Foundation
National Natural Science Foundation of China
High-level Talents-Top Talents Project of Henan Agricultural University
Youth Talent Support Program of Henan Province
Subject
Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Computer Science Applications,Spectroscopy,Molecular Biology,General Medicine,Catalysis