High-Efficiency Reducing Strain for Producing Selenium Nanoparticles Isolated from Marine Sediment
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Published:2022-10-08
Issue:19
Volume:23
Page:11953
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ISSN:1422-0067
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Container-title:International Journal of Molecular Sciences
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language:en
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Short-container-title:IJMS
Author:
Zhang LiyingORCID,
Li Zhuting,
Zhang Lei,
Lei Zhixiao,
Jin Liming,
Cao Jijuan,
Quan Chunshan
Abstract
Selenium nanoparticles (SeNPs) are all important for research because they exhibit a higher degree of absorption and lower toxicity than that of their organic and inorganic forms. At present, there are few reports on marine strains that can reduce Se(IV) to generate Se(0). In this study, a strain that reduces sodium selenite to SeNPs with high efficiency was screened from 40 marine strains. The SeNPs-S produced by the whole cells and SeNPs-E produced by the extracellular extract were characterized by FTIR, UV, Raman, XRD and SEM. Based on the results, the two kinds of SeNPs exhibited obvious differences in morphology, and their surfaces were capped with different biomacromolecules. Due to the difference in shape and surface coating, opposite results were obtained for the antibacterial activity of SeNPs-S and SeNPs-E against Gram-positive and Gram-negative bacteria. Both SeNPs-S and SeNPs-E exhibited no obvious cytotoxicity at concentrations up to 100 μg/mL, but SeNPs-E retained lower cytotoxicity when its concentration increased to 200 μg/mL. This is the first report on the detailed difference between the SeNPs produced by whole cells and cell extracts.
Funder
the key lab of marine bioactive substance and modern analytical technique, SOA
Subject
Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Computer Science Applications,Spectroscopy,Molecular Biology,General Medicine,Catalysis
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