Explainable Convolutional Neural Networks for Brain Cancer Detection and Localisation

Author:

Mercaldo Francesco12ORCID,Brunese Luca1,Martinelli Fabio2,Santone Antonella1,Cesarelli Mario3

Affiliation:

1. Department of Medicine and Health Sciences “Vincenzo Tiberio”, University of Molise, 86100 Campobasso, Italy

2. Institute for Informatics and Telematics, National Research Council of Italy, 56121 Pisa, Italy

3. Department of Engineering, University of Sannio, 82100 Benevento, Italy

Abstract

Brain cancer is widely recognised as one of the most aggressive types of tumors. In fact, approximately 70% of patients diagnosed with this malignant cancer do not survive. In this paper, we propose a method aimed to detect and localise brain cancer, starting from the analysis of magnetic resonance images. The proposed method exploits deep learning, in particular convolutional neural networks and class activation mapping, in order to provide explainability by highlighting the areas of the medical image related to brain cancer (from the model point of view). We evaluate the proposed method with 3000 magnetic resonances using a free available dataset. The results we obtained are encouraging. We reach an accuracy ranging from 97.83% to 99.67% in brain cancer detection by exploiting four different models: VGG16, ResNet50, Alex_Net, and MobileNet, thus showing the effectiveness of the proposed method.

Funder

EU DUCA, EU CyberSecPro, SYNAPSE

EU - NextGenerationEU projects

Publisher

MDPI AG

Subject

Electrical and Electronic Engineering,Biochemistry,Instrumentation,Atomic and Molecular Physics, and Optics,Analytical Chemistry

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