SARS-CoV-2 Genomic Epidemiology Dashboards: A Review of Functionality and Technological Frameworks for the Public Health Response

Author:

Sitharam Nikita1ORCID,Tegally Houriiyah1,Silva Danilo de Castro12,Baxter Cheryl13ORCID,de Oliveira Tulio1345,Xavier Joicymara S.167ORCID

Affiliation:

1. Centre for Epidemic Response and Innovation (CERI), School for Data Science and Computational Thinking, Stellenbosch University, Stellenbosch 7600, South Africa

2. Department of Computer Science, Faculty of Science, Stellenbosch University, Stellenbosch 7600, South Africa

3. Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban 4001, South Africa

4. KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban 4001, South Africa

5. Department of Global Health, University of Washington, Seattle, WA 98105, USA

6. Institute of Agricultural Sciences, Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Unaí 38610-000, Brazil

7. Institute of Biological Sciences, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte 31270-901, Brazil

Abstract

During the coronavirus disease 2019 (COVID-19) pandemic, the number and types of dashboards produced increased to convey complex information using digestible visualizations. The pandemic saw a notable increase in genomic surveillance data, which genomic epidemiology dashboards presented in an easily interpretable manner. These dashboards have the potential to increase the transparency between the scientists producing pathogen genomic data and policymakers, public health stakeholders, and the public. This scoping review discusses the data presented, functional and visual features, and the computational architecture of six publicly available SARS-CoV-2 genomic epidemiology dashboards. We found three main types of genomic epidemiology dashboards: phylogenetic, genomic surveillance, and mutational. We found that data were sourced from different databases, such as GISAID, GenBank, and specific country databases, and these dashboards were produced for specific geographic locations. The key performance indicators and visualization used were specific to the type of genomic epidemiology dashboard. The computational architecture of the dashboards was created according to the needs of the end user. The genomic surveillance of pathogens is set to become a more common tool used to track ongoing and future outbreaks, and genomic epidemiology dashboards are powerful and adaptable resources that can be used in the public health response.

Funder

Centre for Epidemic Response and Innovation

South African Medical Research Council

Rockefeller Foundation

Abbott Pandemic Defense Coalition

National Institute of Health USA

SAMRC South African mRNA Vaccine Consortium

European Union’s Horizon Europe Research and Innovation Programme

Health Emergency Preparedness and Response Umbrella Program (HEPR Program), managed by the World Bank Group

Wellcome Trust for the Global.health project

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior–Brasil

Publisher

MDPI AG

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