Genome-Wide Identification and Bioinformatics Analysis of the FK506 Binding Protein Family in Rice

Author:

Nie Fanhao1,Wang Minghao1,Liu Linlin1,Ma Xuefei1,Zhao Juan1

Affiliation:

1. The Key Laboratory for Quality Improvement of Agricultural Products of Zhejiang Province, College of Advanced Agricultural Sciences, Zhejiang A&F University, Hangzhou 311300, China

Abstract

The FK506 Binding Protein (FKBP), ubiquitously present across diverse species, is characterized by its evolutionarily conserved FK506 binding domain (FKBd). In plants, evidence suggests that this gene family plays integral roles in regulating growth, development, and responses to environmental stresses. Notably, research on the identification and functionality of FKBP genes in rice remains limited. Therefore, this study utilized bioinformatic tools to identify 30 FKBP-encoding genes in rice. It provides a detailed analysis of their chromosomal locations, evolutionary relationships with the Arabidopsis thaliana FKBP family, and gene structures. Further analysis of the promoter elements of these rice FKBP genes revealed a high presence of stress-responsive elements. Quantitative PCR assays under drought and heat stress conditions demonstrated that genes OsFKBP15-2, OsFKBP15-3, OsFKBP16-3, OsFKBP18, and OsFKBP42b are inducible by these adverse conditions. These findings suggest a significant role for the rice FKBP gene family in stress adaptation. This research establishes a critical foundation for deeper explorations of the functional roles of the OsFKBP genes in rice.

Funder

National Natural Science Foundation of China

Zhejiang A & F University

Publisher

MDPI AG

Reference37 articles.

1. Progress and clinical application evaluation of immunosuppressants;Shige;Eval. Anal. Drug-Use Hosp. China,2008

2. Chemistry and biology of the immunophilins and their immunosuppressive ligands;Schreiber;Science,1991

3. Immunophilins in protein folding and immunosuppression;Fruman;FASEB J. Off. Publ. Fed. Am. Soc. Exp. Biol.,1994

4. Atomic structures of the human immunophilin FKBP-12 complexes with FK506 and rapamycin;Standaert;J. Mol. Biol.,1993

5. Genomic organization of mouse and human 65 kDa FK506-binding protein genes and evolution of the FKBP multigene family;Patterson;Genomics,2002

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3