Abstract
Biochemical and biological differences in the venom of Crotalus durissus cumanensis from three ecoregions of Colombia were evaluated. Rattlesnakes were collected from the geographic areas of Magdalena Medio (MM), Caribe (CA) and Orinoquía (OR). All three regionally distributed venoms contain proteases, PLA2s and the basic subunit of crotoxin. However, only crotamine was detected in the CA venom. The highest lethality, coagulant, phospholipase A2 and hyaluronidase activities were found in the MM venom. Also, some differences, observed by western blot and immunoaffinity, were found in all three venoms when using commercial antivenoms. Furthermore, all three eco-regional venoms showed intraspecific variability, considering the differences in the abundance and intensity of their components, in addition to the activity and response to commercial antivenoms.
Subject
Health, Toxicology and Mutagenesis,Toxicology
Reference116 articles.
1. The Reptile Databasehttps://reptile-database.reptarium.cz/species?genus=Crotalus&species=durissus
2. El contexto de las serpientes de Colombia con un análisis de las amenazas en contra de su conservación;Lynch;Rev. Acad. Colomb.,2012
3. Ofidismo en Colombia. Enfoque, diagnóstico y tratamiento;Ayerbe,2009
4. Programa Nacional para la Conservación de las Serpientes Presentes en Colombia;Lynch,2014
5. Accessing cryptic diversity in Neotropical rattlesnakes (Serpentes: Viperidae: Crotalus) with the description of two new species
Cited by
4 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献