PET Imaging in Bladder Cancer: An Update and Future Direction

Author:

Zhang-Yin Jules1ORCID,Girard Antoine2,Marchal Etienne2,Lebret Thierry3,Homo Seban Marie4,Uhl Marine5,Bertaux Marc4ORCID

Affiliation:

1. Department of Nuclear Medicine, Clinique Sud Luxembourg, Vivalia, B-6700 Arlon, Belgium

2. Department of Nuclear Medicine, Amiens-Picardy University Hospital, 80054 Amiens, France

3. Department of Urology, Foch Hospital, 92150 Suresnes, France

4. Department of Nuclear Medicine, Foch Hospital, 92150 Suresnes, France

5. Department of Urology and Renal Transplantation, Amiens-Picardy University Hospital, 80054 Amiens, France

Abstract

Molecular imaging with positron emission tomography is a powerful tool in bladder cancer management. In this review, we aim to address the current place of the PET imaging in bladder cancer care and offer perspectives on potential future radiopharmaceutical and technological advancements. A special focus is given to the following: the role of [18F] 2-[18F]fluoro-2-deoxy-D-glucose positron emission tomography in the clinical management of bladder cancer patients, especially for staging and follow-up; treatment guided by [18F]FDG PET/CT; the role of [18F]FDG PET/MRI, the other PET radiopharmaceuticals beyond [18F]FDG, such as [68Ga]- or [18F]-labeled fibroblast activation protein inhibitor; and the application of artificial intelligence.

Publisher

MDPI AG

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

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