A Narrative Review of the Herbal Preparation of Ayurvedic, Traditional Chinese, and Kampō Medicines Applied as Radioprotectors

Author:

Ibáñez Blanca1,Melero Ana2ORCID,Montoro Alegría34ORCID,Merino-Torres Juan F.567ORCID,Soriano Jose M.15ORCID,San Onofre Nadia18ORCID

Affiliation:

1. Food & Health Laboratory, Institute of Materials Science, University of Valencia, 46980 Paterna, Spain

2. Department of Pharmacy and Pharmaceutical Technology and Parasitology, Faculty of Pharmacy, University of Valencia, 46100 Burjassot, Spain

3. Service of Radiological Protection, Clinical Area of Medical Image, University and Polytechnic La Fe Hospital, 46026 Valencia, Spain

4. Biomedical Imaging Research Group GIBI230, Health Research Institute (IISLaFe), University and Polytechnic La Fe Hospital, 46026 Valencia, Spain

5. Joint Research Unit on Endocrinology, Nutrition and Clinical Dietetics, Health Research Institute La Fe, University of Valencia, 46026 Valencia, Spain

6. Department of Endocrinology and Nutrition, University and Polytechnic La Fe Hospital, 46026 Valencia, Spain

7. Department of Medicine, Faculty of Medicine, University of Valencia, 46010 Valencia, Spain

8. Department of Community Nursing, Preventive Medicine and Public Health and History of Science, University of Alicante, 03690 Alicante, Spain

Abstract

In recent years, there has been growing scientific interest in the search for natural radioprotectors that can be used to mitigate the effects of radiation on patients, healthcare personnel, and even for space travel. This narrative review covers the past fifty years and focuses on herbal preparations of Ayurvedic, Traditional Chinese, and Kampō Medicines that have the potential to reduce or eliminate the harmful effects of radiation. Our findings highlight ten herbal preparations, namely Abana, Amalakyadi Churna, Amritaprasham, Brahma, Bu-zhong-yi-qi-tang (BZYQT), Chyavanaprasha, Cystone, Geriforte, Mentat, and Triphala, which have demonstrated potential radioprotective effects. This review examines their composition, properties, and possible mechanisms of action in relation to their radioprotective properties. Exploring the ethnobotany of traditional Asian medicine is particularly interesting as it may lead to the discovery of new active compounds with radioprotective properties.

Funder

Spanish Nuclear Safety Council

University of Valencia and Generalitat Valenciana

Universidad de Alicante, Ministerio de Universidades and the European Union “NextGeneration EU/PRTR”

Publisher

MDPI AG

Subject

Cell Biology,Clinical Biochemistry,Molecular Biology,Biochemistry,Physiology

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