Superoxide-Mediated Upregulation of MMP9 Participates in BMPR2 Destabilization and Pulmonary Hypertension Development
Author:
Affiliation:
1. Department of Physiology, New York Medical College, Valhalla, NY 10595, USA
2. Department of Basic Sciences, College of Science and Health Professions, King Saud Bin Abdulaziz for Health Sciences, Riyadh 11481, Saudi Arabia
Abstract
Funder
NIH Grants
Publisher
MDPI AG
Subject
Cell Biology,Clinical Biochemistry,Molecular Biology,Biochemistry,Physiology
Link
https://www.mdpi.com/2076-3921/12/11/1961/pdf
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2. Potential role of cartilage oligomeric matrix protein in the modulation of pulmonary arterial smooth muscle superoxide by hypoxia;Yu;Am. J. Physiol. Lung Cell Mol. Physiol.,2019
3. Endothelin-1 depletion of cartilage oligomeric matrix protein modulates pulmonary artery superoxide and iron metabolism-associated mitochondrial heme biosynthesis;Yu;Am. J. Physiol. Lung Cell Mol. Physiol.,2022
4. Reactive oxygen and nitrogen species in pulmonary hypertension;Tabima;Free Radic. Biol. Med.,2012
5. The IRE1α-XBP1 pathway function in hypoxia-induced pulmonary vascular remodeling, is upregulated by quercetin, inhibits apoptosis and partially reverses the effect of quercetin in PASMCs;Cao;Am. J. Transl. Res.,2019
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