Complex Mixture of Arvensic Acids Isolated from Convolvulus arvensis Roots Identified as Inhibitors of Radicle Growth of Broomrape Weeds

Abstract

Broomrape weeds (Orobanche and Phelipanche spp.) are noxious parasites that infect crops using haustoria formed at the tip of their radicles. Dichloromethane extract obtained from the roots of Convolvulus arvensis strongly inhibits the radicle growth of broomrape weeds. A complex mixture of arvensic acids was isolated as the metabolites responsible of the inhibitory activity of C. arvensis extract against broomrape radicle growth via activity-guided fractionation and 1H NMR and ESI MS data. We showed that the exposure of broomrape seedlings to this arvensic acids mixture results in a strong phytotoxic effect on their radicles in four broomrape species infecting a wide range of crops worldwide. This discovery paves the way for the synthesis of new bioherbicides and could contribute to the development of efficient and sustainable management strategies for broomrape weeds, for which control in many crops is limited or non-existing.