Investigating the Impact of Dietary Fibers on Mycotoxin Bioaccessibility during In Vitro Biscuit Digestion and Metabolites Identification
Author:
López-Ruiz Rosalía12ORCID, Marin-Saez Jesús12ORCID, Cunha Sara. C.1ORCID, Fernandes Ana3ORCID, de Freitas Victor3, Viegas Olga14ORCID, Ferreira Isabel M. P. L. V. O.1ORCID
Affiliation:
1. LAQV/REQUIMTE, Laboratory of Bromatology and Hydrology, Department of Chemical Sciences, Porto University, 4050-313 Porto, Portugal 2. Research Group “Analytical Chemistry of Contaminants”, Department of Chemistry and Physics, Research Centre for Mediterranean Intensive Agrosystems and Agri-Food Biotechnology (CIAIMBITAL), University of Almeria, Agrifood Campus of International Excellence, ceiA3, E-04120 Almeria, Spain 3. LAQV/REQUIMTE, Department of Chemistry and Biochemistry, Science Faculty, Porto University, 4169-007 Porto, Portugal 4. Faculty of Nutrition and Food Sciences, University of Porto, 4150-180 Porto, Portugal
Abstract
Mycotoxins contamination is a real concern worldwide due to their high prevalence in foods and high toxicity; therefore, strategies that reduce their gastrointestinal bioaccessibility and absorption are of major relevance. The use of dietary fibers as binders of four mycotoxins (zearalenone (ZEA), deoxynivalenol (DON), HT-2, and T-2 toxins) to reduce their bioaccessibility was investigated by in vitro digestion of biscuits enriched with fibers. K-carrageenan is a promising fiber to reduce the bioaccessibility of ZEA, obtaining values lower than 20%, while with pectin a higher reduction of DON, HT-2, and T-2 (50–88%) was achieved. Three metabolites of mycotoxins were detected, of which the most important was T-2-triol, which was detected at higher levels compared to T-2. This work has demonstrated the advantages of incorporating dietary fibers into a biscuit recipe to reduce the bioaccessibility of mycotoxins and to obtain healthier biscuits than when a conventional recipe is performed due to its high content of fiber.
Funder
DIETxPOSOME project FCT/MCTES Ayudas para Captación, Incorporación y Movilidad de Capital Humano de I+D+i European Regional Development Fund European Union
Subject
Plant Science,Health Professions (miscellaneous),Health (social science),Microbiology,Food Science
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