2D Spatially-Resolved Depth-Section Microfluidic Flow Velocimetry Using Dual Beam OCT
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Published:2020-03-27
Issue:4
Volume:11
Page:351
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ISSN:2072-666X
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Container-title:Micromachines
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language:en
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Short-container-title:Micromachines
Author:
Hallam Jonathan M.ORCID,
Rigas EvangelosORCID,
Charrett Thomas O. H.ORCID,
Tatam Ralph P.
Abstract
A dual beam optical coherence tomography (OCT) instrument has been developed for flow measurement that offers advantages over microscope derived imaging techniques. It requires only a single optical access port, allows simultaneous imaging of the microfluidic channel, does not require fluorescent seed particles, and can provide a millimetre-deep depth-section velocity profile (as opposed to horizontal-section). The dual beam instrument performs rapid re-sampling of particle positions, allowing measurement of faster flows. In this paper, we develop the methods and processes necessary to make 2D quantitative measurements of the flow-velocity using dual beam OCT and present exemplar results in a microfluidic chip. A 2D reference measurement of the Poiseuille flow in a microfluidic channel is presented over a spanwise depth range of 700 m and streamwise length of 1600 m with a spatial resolution of 10 m , at velocities up to 50 m m / s . A measurement of a more complex flow field is also demonstrated in a sloped microfluidic section.
Funder
Engineering and Physical Sciences Research Council
Subject
Electrical and Electronic Engineering,Mechanical Engineering,Control and Systems Engineering
Cited by
1 articles.
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1. 激光诱发荧光漂白测速技术的发展与应用(特邀);ACTA PHOTONICA SINICA;2022