First Report of Marek’s Disease Virus in Commercial Turkeys in Slovenia-Reference-Cited by-同舟云学术

First Report of Marek’s Disease Virus in Commercial Turkeys in Slovenia

Published:2024-01-12 Issue:2 Volume:14 Page:250
ISSN:2076-2615
Container-title:Animals
language:en
Short-container-title:Animals

Author:

Žlabravec Zoran¹^ORCID,Slavec Brigita¹,Rožmanec Ema²,Koprivec Saša³,Dovč Alenka¹^ORCID,Zorman Rojs Olga¹

Affiliation:

1. Institute of Poultry, Birds, Small Mammals, and Reptiles, Faculty of Veterinary Medicine, University of Ljubljana, Gerbičeva ulica 60, 1000 Ljubljana, Slovenia

2. Veterinarska Ambulanta PP, d.o.o., Potrčeva cesta 10, 2250 Ptuj, Slovenia

3. Institute of Preclinical Sciences, Faculty of Veterinary Medicine, University of Ljubljana, Gerbičeva ulica 60, 1000 Ljubljana, Slovenia

Abstract

Marek’s disease (MD), caused by Mardivirus gallidalpha 2 (GaAHV-2), also known as MD virus (MDV), is a lymphoproliferative disease that primarily affects chickens. Recently, MDV has been detected in lymphomatous tumors in turkeys in various countries. Between 2021 and 2023, three cases ranging from no to severe clinical disorders (depression, lameness, and increased mortality) occurred in commercial turkey flocks in Slovenia. In all cases, MDV was detected by PCR in DNA samples extracted from organs developing tumor infiltrations. Sequencing and phylogenetic analysis of the meq gene revealed that the GaAHV-2 detected has molecular features of a very virulent pathotype and genetic similarity with GaAHV-2 detected in chickens in Tunisia. This is the first report of MDV in commercial turkeys in Slovenia.

Funder

Environment and Food Safety, Ministry of Agriculture, Forestry and Food

Publisher

MDPI AG

Link

https://www.mdpi.com/2076-2615/14/2/250/pdf

Reference36 articles.

1. Neoplastic diseases;Swayne;Diseases of Poultry,2020

2. The order Herpesvirales;Davison;Arch. Virol.,2019

3. Marek’s disease in commercial turkey flocks;Baigent;Vet. Rec.,2013

4. Abdul-Aziz, T., and Barnes, H.J. (2018). Gross Pathology of Avian Diseases: Text and Atlas, The American Association of Avian Pathologists.

5. Classification of Marek’s disease viruses according to pathotype: Philosophy and methodology;Witter;Avian Pathol.,2005

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Specific Glycoprotein E (gE) Gene Based Nested Polymerase Chain Reaction Assay for Detection of Marek’s Disease Virus in Chickens;Agricultural Research;2024-09-02