Abstract
Intravascular large B-cell Lymphoma (IVLBCL) is a rare subtype of extranodal non-Hodgkin’s lymphoma that is challenging to diagnose and has a poor prognosis. Here, we describe two patients newly diagnosed with IVLBCL at our institution: an African man with hemophagocytic-syndrome-associated IVLBCL and an Italian woman with a cutaneous variant of IVLBCL. They presented with very different clinical manifestations. Both cases were diagnosed in a timely manner, successfully treated, and achieved long-lasting remissions.
Reference25 articles.
1. Swerdlow, S.H., Campo, E., Pileri, S.A., Harris, N.L., Stein, H., Siebert, R., Advani, R., Ghielmini, M., Salles, G.A., and Zelenetz, A.D. (2022, May 22). Review Series the Updated who Classification of Hematological Malignancies the 2016 Revision of the World Health Organization Classification of Lymphoid Neoplasms. Available online: http://ashpublications.org/blood/article-pdf/127/20/2375/1393632/2375.pdf.
2. Ponzoni, M., Campo, E., and Nakamura, S. (2022, May 22). Intravascular Large B-Cell Lymphoma: A Chameleon with Multiple Faces and Many Masks. Available online: http://ashpublications.org/blood/article-pdf/132/15/1561/1406631/blood737445.pdf.
3. Diagnosis of intravascular large B cell lymphoma: Novel insights into clinicopathological features from 42 patients at a single institution over 20 years;Matsue;Br. J. Haematol.,2019
4. A Case of De Novo CD5+ Disseminated Intravascular Large B-Cell Lymphoma Presenting as Multiorgan Failure;Singh;Case Rep. Hematol.,2016
5. Definition, diagnosis, and management of intravascular large B-cell lymphoma: Proposals and perspectives from an international consensus meeting;Ponzoni;J. Clin. Oncol.,2007