Cyclodextrins for the Delivery of Bioactive Compounds from Natural Sources: Medicinal, Food and Cosmetics Applications

Author:

Christaki Stamatia1ORCID,Spanidi Eleni2,Panagiotidou Eleni2,Athanasopoulou Sophia2,Kyriakoudi Anastasia1,Mourtzinos Ioannis1ORCID,Gardikis Konstantinos2

Affiliation:

1. Laboratory of Food Chemistry and Biochemistry, School of Agriculture, Aristotle University of Thessaloniki (AUTH), 54124 Thessaloniki, Greece

2. APIVITA SA, Industrial Park, Markopoulo, 19003 Athens, Greece

Abstract

Cyclodextrins have gained significant and established attention as versatile carriers for the delivery of bioactive compounds derived from natural sources in various applications, including medicine, food and cosmetics. Their toroidal structure and hydrophobic cavity render them ideal candidates for encapsulating and solubilizing hydrophobic and poorly soluble compounds. Most medicinal, food and cosmetic ingredients share the challenges of hydrophobicity and degradation that can be effectively addressed by various cyclodextrin types. Though not new or novel—their first applications appeared in the market in the 1970s—their versatility has inspired numerous developments, either on the academic or industrial level. This review article provides an overview of the ever-growing applications of cyclodextrins in the delivery of bioactive compounds from natural sources and their potential application benefits.

Publisher

MDPI AG

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

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