Abstract
The rise of primary topical monotherapy with chemotherapeutic drugs and immunomodulatory agents represents an increasing recognition of the medical management of ocular surface squamous neoplasia (OSSN), which may replace surgery as the standard of care in the future. Currently, there is no consensus regarding the best way to manage OSSN with no existing guidelines to date. This paper seeks to evaluate evidence surrounding available treatment modalities and proposes an approach to management. The approach will guide ophthalmologists in selecting the most appropriate treatment regime based on patient and disease factors to minimize treatment related morbidity and improve OSSN control. Further work can be done to validate this algorithm and to develop formal guidelines to direct the management of OSSN.
Subject
Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Computer Science Applications,Spectroscopy,Molecular Biology,General Medicine,Catalysis
Reference167 articles.
1. Ocular Surface Squamous Neoplasia;Lee;Surv. Ophthalmol.,1995
2. Epidemiology of Ocular Surface Squamous Neoplasia in Africa;Gichuhi;Trop. Med. Int. Health,2013
3. Retrospective Study of Ocular Surface Squamous Neoplasia;Lee;Aust. N. Z. J. Ophthalmol.,1997
4. Factors Associated with Conjunctival Intraepithelial Neoplasia: A Case Control Study;Napora;Ophthalmic Surg.,1990
5. Risk Factors for Ocular Surface Squamous Neoplasia in Kenya: A Case-Control Study;Gichuhi;Trop. Med. Int. Health,2016
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