Abstract
Magnesium (Mg) is involved in the regulation of metabolism and in the maintenance of the homeostasis of all the tissues, including the brain, where it harmonizes nerve signal transmission and preserves the integrity of the blood–brain barrier. Mg deficiency contributes to systemic low-grade inflammation, the common denominator of most diseases. In particular, neuroinflammation is the hallmark of neurodegenerative disorders. Starting from a rapid overview on the role of magnesium in the brain, this narrative review provides evidences linking the derangement of magnesium balance with multiple sclerosis, Alzheimer’s, and Parkinson’s diseases.
Subject
Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Computer Science Applications,Spectroscopy,Molecular Biology,General Medicine,Catalysis
Reference131 articles.
1. The significance of Mg in prebiotic geochemistry;Holm;Geobiology,2012
2. ’Magnesium’-the master cation-as a drug-possibilities and evidences;Mathew;Biometals,2021
3. The relevance of magnesium homeostasis in COVID-19;Trapani;Eur. J. Nutr.,2022
4. Magnesium and inflammation: Advances and perspectives;Maier;Semin. Cell Dev. Biol.,2021
5. Benzodiazepine/GABA(A) receptors are involved in magnesium-induced anxiolytic-like behavior in mice;Poleszak;Pharmacol. Rep.,2008
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