Impact of Clinical Pharmacist Running Anticoagulation Clinic in Saudi Arabia
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Published:2023-06-07
Issue:12
Volume:12
Page:3887
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ISSN:2077-0383
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Container-title:Journal of Clinical Medicine
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language:en
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Short-container-title:JCM
Author:
Alshaiban Abdulrahman1, Alavudeen Sirajudeen S.2, Alshahrani Ibrahim1, Kardam Abdulaziz M.1ORCID, Alhasan Ibrahim Mohammed1, Alasiri Saleh Abdulrahman1, Imam Mohammad Tarique3ORCID, Almalki Ziyad Saeed3ORCID, Akhtar Md Sayeed2ORCID
Affiliation:
1. King Faisal Medical City, Ministry of Health, Abha 62521, Saudi Arabia 2. Department of Clinical Pharmacy, College of Pharmacy, King Khalid University, Al-Fara, Abha 62223, Saudi Arabia 3. Department of Clinical Pharmacy, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj 16273, Saudi Arabia
Abstract
Despite the effectiveness of warfarin in extended anticoagulation, its narrow therapeutic index requires frequent dose adjustments and careful patient monitoring. Thus, we aimed to evaluate the outcomes of clinical pharmacists’ intervention in warfarin therapy management in terms of International Normalized Ratio (INR) control, reduction of bleeding, and hospitalization in a tertiary care hospital. An observational retrospective cohort study was conducted on 96 patients taking warfarin therapy in a clinical pharmacist-led anticoagulation clinic. We observed that 39.6% of patients required dose adjustments at their first and second visits. However, dose adjustments during the third, fourth, and fifth weeks were required at 31.1%, 20.8%, and 4.2%, respectively, to achieve INR levels. We also observed that 36.46% of the patients attained the target INR at baseline, which was increased over the first week to the fifth week to 57.29%, 61.46%, 61.46%, 68.75%, and 85.42%, respectively. No one reported the ADR between the third and fifth weeks. Based on our findings, the study strongly suggests that pharmacists’ interventions can improve the health-related quality of life of patients undergoing warfarin therapy. Thus, competent pharmacy personnel must be a priority in both usual patient care and critical care among primary care networks.
Funder
King Khalid University
Reference42 articles.
1. (2023, April 13). Centers for Disease Control and Prevention Heart Disease Facts, Available online: https://www.cdc.gov/heartdisease/facts.htm. 2. Heart Disease and Stroke Statistics-2022 Update: A Report from the American Heart Association;Tsao;Circulation,2022 3. The Pharmacology and Management of the Vitamin K Antagonists: The Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy;Ansell;Chest,2004 4. Koda-Kimble, M.A., Young, L.Y., Kradjan, W.A., Guglielmo, B.J., Alldredge, B.K., Corelli, R.L., and Williams, B.R. (2008). Applied Therapeutics: The Clinical Use of Drugs, Lippincott Williams and Wilkins. [9th ed.]. 5. Chisholm-Burns, M.A., Schwinghammer, T.L., Wells, B.G., Malone, P.M., and DiPiro, J.T. (2013). Pharmacotherapy Principles and Practice, McGraw-Hill Medical. [3rd ed.].
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