BMI Impact on Readmissions for Patients Undergoing Robot-Assisted Radical Prostatectomy: A Monocentric, Single-Surgeon Serial Analysis of 500 Cases

Author:

Farzat Mahmoud12ORCID,Sharabaty Ismail1,Tanislav Christian3,Alsaid Yaman4,Wagenlehner Florian M.2ORCID

Affiliation:

1. Department of Robotic Urology, Diakonie Klinikum Siegen, Academic Teaching Hospital, University of Bonn, 53127 Bonn, Germany

2. Department of Urology, Pediatric Urology and Andrology, Justus-Liebig University of Giessen, 35390 Giessen, Germany

3. Department of Geriatric and Neurology, Diakonie Klinkum Siegen, Academic Teaching Hospital, University of Bonn, 53127 Bonn, Germany

4. Department of Urology, St. Josef Hospital Engelskirchen, 51766 Engelskirchen, Germany

Abstract

Due to more difficult intraoperative courses, elevated rates of case abortion and unfavored postoperative outcomes in obese patients, urologists tend to consider other therapeutic modalities than prostate removal in very obese patients. With the surge in robotic surgery in the last two decades, more obese patients have undergone robot-assisted radical prostatectomy (RARP). Objective: This current, monocentric, retrospective serial study investigates primarily the impact of obesity on readmissions and secondarily the major complications of RARP. Methods: Five hundred patients from one referral center who underwent RARP between April 2019 and August 2022 were included in this retrospective study. To investigate the impact of patient BMI on postoperative outcomes, we divided our cohort into two groups with a cut-off of 30 kg/m2 (according to the WHO definition). Demographic and perioperative data were analyzed. Postoperative complications and readmission rates were compared between standard, normal patients (NOBMI—BMI under 30; n = 336, 67.2%) and overweight patients (OBMI—BMI equal to/more than 30; n = 164, 32.8%). Results: OBMI patients had bigger prostates on TRUS, more comorbidities and worse baseline erectile function scores. They also received fewer nerve-sparing procedures than their counterparts (p = 0.005). Analysis showed no statistically significant differences in readmission rates or in minor or major complications (p = 0.336, 0.464 and 0.316, respectively). In a univariate analysis, BMI could predict positive surgical margins (p = 0.021). Conclusion: Performing RARP in obese patients seems to be safe and feasible, without major adverse events or elevated readmission rates. Obese patients should be informed preoperatively about the elevated risk of higher PSMs and technically more difficult nerve-sparing procedures.

Publisher

MDPI AG

Subject

General Medicine

Reference23 articles.

1. Robotic radical prostatectomy in overweight and obese patients: Oncological and validated-functional outcomes;Wiltz;Urology,2009

2. Obesity leads to a higher rate of positive surgical margins in the context of robot-assisted radical prostatectomy. Results of a prospective multicenter study;May;Cent. Eur. J. Urol.,2020

3. Clinical factors affecting perioperative outcomes in robot-assisted radical prostatectomy;Murakami;Mol. Clin. Oncol.,2018

4. Efficacy of a weight loss program prior to robot assisted radical prostatectomy in overweight and obese men with prostate cancer;Wilson;Surg. Oncol.,2020

5. Aggressive Tumours and Long Console Time Are Independent Predictive Factors for Symptomatic Lymphocele Formation after Robot-Assisted Radical Prostatectomy and Pelvic Lymph Node Dissection;May;Urol. Int.,2021

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