Alliaceae-Derived Supplementation Improves the Severity of COVID-19 Symptoms among Elderly Nursing Home Residents

Author:

Vázquez-Blanquiño Alberto1,Pérez-Rodríguez Lucía1ORCID,Alberola-Romano Ana1ORCID,Martínez-Pérez María2,Baños Alberto3ORCID,Gómez-Fernández Germán O.4ORCID,Gracián Carlos5,Fonollá Juristo6,García Federico178ORCID

Affiliation:

1. Clinical Microbiology Department, Hospital Universitario Clínico San Cecilio, 18016 Granada, Spain

2. Pharmacy Department, Hospital Universitario Clínico San Cecilio, 18016 Granada, Spain

3. DMC Research Center, Camino de Jayena, 82, 18620 Granada, Spain

4. Department of Sciences, Public University of Navarra, 31006 Pamplona, Spain

5. Nursing Home “Residencia de Mayores Claret”, 18011 Granada, Spain

6. Department of Nutrition and Food Technology, University of Granada, 18071 Granada, Spain

7. Instituto de Investigación Biosanitaria (ibs.GRANADA), 18014 Granada, Spain

8. Centro de Investigación Biomédica en Red en Enfermedades Infecciosas (CIBERINFEC), ISCIII, 28029 Madrid, Spain

Abstract

This study investigates the effect of daily consumption of a concentrated garlic and onion extract on COVID-19 symptoms among elderly nursing home residents. Volunteers consumed a daily capsule of the concentrated powder rich in organosulfur compounds over 36 weeks during lunch. The incidence and severity of COVID-19 symptoms between the treatment and control groups were compared, along with monitoring the safety of consumption, incidence of other diseases, and medicine usage. The treatment group showed a significant reduction in both the number and severity of COVID-19 symptoms compared to the control group, with no significant adverse effects observed. No significant reduction in symptom duration was detected. This study provides preliminary evidence that concentrated garlic and onion extract may aid in the treatment of COVID-19 among older adults. These findings suggest potential public health benefits, emphasizing the need for further research to explore the immunomodulatory properties of these natural compounds.

Funder

FEDER-INNTERCONECTA-CDTI program CDTI, Centre for the Development of Industrial Technology; NATURPICK Project

Publisher

MDPI AG

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3. Agencia Española de Medicamentos y Productos Sanitarios. (n.d.) (2024, June 13). Criterios Para Valorar la Administración de las Nuevas Alternativas Terapéuticas Antivirales Frente a la Infección por SARS-CoV-2, Available online: https://www.aemps.gob.es/medicamentos-de-uso-humano/acceso-a-medicamentos-en-situaciones-especiales/criterios-para-valorar-la-administracion-de-las-nuevas-alternativas-terapeuticas-antivirales-frente-a-la-infeccion-por-sars-cov-2/.

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