Affiliation:
1. Department of Industrial Pharmacy, Faculty of Pharmacy, Silpakorn University, Nakhon Pathom 73000, Thailand
2. Natural Products Research Center (NPRC), Faculty of Pharmacy, Silpakorn University, Nakhon Pathom 73000, Thailand
Abstract
This study aimed to develop a high-quality dry emulsion incorporating omega-3, 6, and 9 fatty acid-rich ostrich oil for use as a dietary supplement. Extracted from abdominal adipose tissues using a low-temperature wet rendering method, the ostrich oil exhibited antioxidant properties, favorable physicochemical properties, microbial counts, heavy metal levels, and fatty acid compositions, positioning it as a suitable candidate for an oil-in-water emulsion and subsequent formulation as a dry emulsion. Lecithin was employed as the emulsifier due to its safety and health benefits. The resulting emulsion, comprising 10% w/w lecithin and 10% w/w ostrich oil, was stable, with a droplet size of 3.93 ± 0.11 μm. This liquid emulsion underwent transformation into a dry emulsion to preserve the physicochemical stability of ostrich oil, utilizing Avicel® PH-101 or Aerosil® 200 through a granulation process. Although Aerosil® 200 exhibited superior adsorption, Avicel® PH-101 granules surpassed it in releasing the ostrich oil emulsion. Consequently, Avicel® PH-101 was selected as the preferred adsorbent for formulating the ostrich oil dry emulsion. The dry emulsion, encapsulated with a disintegration time of 3.11 ± 0.14 min for ease of swallowing, maintained microbial loads and heavy metal contents within acceptable limits. Presented as granules containing butylated hydroxytoluene, the dry emulsion showcased robust temperature stability, suggesting the potential incorporation of animal fat into dry emulsions as a promising dietary supplement.
Funder
Silpakorn University under the Postdoctoral fellowship program
Reference54 articles.
1. Studies on ostrich (Struthio camelus)—Review;Acta Agrar. Debr.,2020
2. Extraction of fat/oil from fleshing by-product using a wet rendering process and combination with organic solvents;Sugihartono;MKKP,2019
3. Assessment of rancidity and other physicochemical properties of edible oils (mustard and corn oils) stored at room temperature;Okparanta;J. Food Nutr. Sci.,2018
4. Determination of heavy metals in herbal drinks using ICP-MS;Limmatvapirat;Adv. Mat. Res.,2014
5. Horbańczuk, O.K., Moczkowska, M., Marchewka, J., Atanasov, A.G., and Kurek, M.A. (2019). The composition of fatty acids in ostrich meat influenced by the type of packaging and refrigerated storage. Molecules, 24.