Antibacterial Activities of Agaricus bisporus Extracts and Their Synergistic Effects with the Antistaphylococcal Drug AFN-1252-Reference-Cited by-同舟云学术

Antibacterial Activities of Agaricus bisporus Extracts and Their Synergistic Effects with the Antistaphylococcal Drug AFN-1252

Published:2024-05-30 Issue:11 Volume:13 Page:1715
ISSN:2304-8158
Container-title:Foods
language:en
Short-container-title:Foods

Author:

Jankov Milica¹^ORCID,Léguillier Vincent²,Gašić Uroš³,Anba-Mondoloni Jamila²,Ristivojević Maja Krstić⁴^ORCID,Radoičić Aleksandra¹^ORCID,Dimkić Ivica⁵^ORCID,Ristivojević Petar⁶,Vidic Jasmina²^ORCID

Affiliation:

1. Innovative Centre of the Faculty of Chemistry Ltd., Studentski trg 12-16, 11158 Belgrade, Serbia

2. Micalis, AgroParisTech, National Research Institute for Agriculture, Food and the Environment (INRAE), University Paris-Saclay, UMR 1319, 78350 Jouy en Josas, France

3. Department of Plant Physiology, Institute for Biological Research “Siniša Stanković”—National Institute of the Republic of Serbia, University of Belgrade, Bulevar despota Stefana 142, 11108 Belgrade, Serbia

4. Department of Biochemistry, Centre of Excellence for Molecular Food Sciences, University of Belgrade, Studentski trg 12-16, 11000 Belgrade, Serbia

5. Department of Biochemistry and Molecular Biology, Faculty of Biology, University of Belgrade, Studentski trg 16, 11158 Belgrade, Serbia

6. Department of Analytical Chemistry, Centre of Excellence for Molecular Food Sciences, University of Belgrade, Studentski trg 12-16, 11000 Belgrade, Serbia

Abstract

Agaricus bisporus, commonly known as the button mushroom, has attracted attention for its biological properties, including antimicrobial activities. Here, we evaluated the efficacy of ethanolic and acetonic extracts from white and brown A. bisporus against different bacterial strains, including antibiotic-resistant strains. Bioautography and principal component analysis identified the most active antibacterial compounds for each of the tested bacteria and indicated the main markers responsible for the strain-specific effects. In addition, the mushroom extracts demonstrated a synergistic impact when combined with the antistaphylococcal antibiotic AFN-1252.

Funder

European Union’s Horizon 2020 research and innovation programme

The Science Fund of the Republic of Serbia, the Serbian Science and Diaspora Collaboration Program

Ministry of Science, Technological Development and Innovation of Republic of Serbia

Conseil Régional d’Ile-de-France

Publisher

MDPI AG

Link

https://www.mdpi.com/2304-8158/13/11/1715/pdf

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