Detecting Airborne Pathogens: A Computational Approach Utilizing Surface Acoustic Wave Sensors for Microorganism Detection

Abstract

The persistent threat posed by infectious pathogens remains a formidable challenge for humanity. Rapidly spreading infectious diseases caused by airborne microorganisms have far-reaching global consequences, imposing substantial costs on society. While various detection technologies have emerged, including biochemical, immunological, and molecular approaches, these methods still exhibit significant limitations such as time-intensive procedures, instability, and the need for specialized operators. This study presents an innovative solution that harnesses the potential of surface acoustic wave (SAW) sensors for the detection of airborne microorganisms. The research involves the establishment of a sensor model within the framework of COMSOL Multiphysics, utilizing a predefined piezoelectric multi-physics interface and employing a 2D modeling approach. Chitosan, selected as the sensing film for the model, interfaces with lithium niobate (LiNbO3), the chosen piezoelectric material responsible for detecting airborne pathogens. The analysis of microbe presence centers on solid displacement and electric potential frequencies, operating within the 850–900 MHz range. Notably, the first and second resonant frequencies are identified at 856 and 859 MHz, respectively. To enhance understanding, this study proposes a novel mathematical model grounded in Stokes’ Law and mass balance equations. This model serves to analyze microbe concentration, offering a fresh perspective on quantifying the presence of airborne pathogens. Through these endeavors, this research contributes to advancing the field of airborne microorganism detection, offering a promising avenue for addressing the challenges posed by infectious diseases.