Pd/DNA as Highly Active and Recyclable Catalyst of Suzuki–Miyaura Coupling

Abstract

Pd/DNA catalysts were prepared in a mixed H2O/EtOH solvent using palladium precursors, Pd(OAc)2 and PdCl2, in different dosages and salmon fish sperm DNA. As prepared, the Pd/DNA contained Pd(II) and Pd(0) nanoparticles of various sizes and morphologies, depending on the preparation method. Pd/DNA efficiently catalyzed the Suzuki–Miyaura cross-coupling of various aryl bromides with phenylboronic acids. The catalyst was recovered by simple phase separation and then reused in seven consecutive cycles with a high activity.