CMR Mapping: The 4th-Era Revolution in Cardiac Imaging

Author:

Carrabba Nazario1ORCID,Amico Mattia Alexis1,Guaricci Andrea Igoren2ORCID,Carella Maria Cristina2,Maestrini Viviana34ORCID,Monosilio Sara34,Pedrotti Patrizia5ORCID,Ricci Fabrizio6ORCID,Monti Lorenzo7ORCID,Figliozzi Stefano7ORCID,Torlasco Camilla8ORCID,Barison Andrea9ORCID,Baggiano Andrea1011ORCID,Scatteia Alessandra12,Pontone Gianluca1011ORCID,Dellegrottaglie Santo12ORCID

Affiliation:

1. Cardio-Thoraco-Vascular Department, Careggi Hospital, 50134 Florence, Italy

2. University Cardiology Unit, Interdisciplinary Department of Medicine, University of Bari Aldo Moro, 70121 Bari, Italy

3. Department of Clinical, Anestesiological and Cardiovascular Science, Sapienza University of Rome, 00185 Rome, Italy

4. Institute of Sports Medicine and Science of Rome, Comitato Olimpico Nazionale Italiano (CONI), 00197 Rome, Italy

5. S.S. Cardiologia Diagnostica per Immagini—RM Cardiaca; S.C. Cardiologia 4 Diagnostica-Riabilitativa Dipartimento CardioToracoVascolare “De Gasperis”, ASST Grande Ospedale Metropolitano Niguarda, 20162 Milano, Italy

6. Department of Neuroscience, Imaging and Clinical Sciences, G. d’Annunzio University of Chieti-Pescara, 66100 Chieti, Italy

7. IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, 20089 Milan, Italy

8. Department of Cardiovascular, Neural and Metabolic Sciences, IRCCS Istituto Auxologico Italiano, 20165 Milan, Italy

9. Fondazione Toscana Gabriele Monasterio, 56127 Pisa, Italy

10. Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, 20138 Milan, Italy

11. Department of Biomedical, Surgical and Dental Sciences, University of Milan, 20133 Milan, Italy

12. Cardiovascular MRI Laboratory, Unit of Advanced Cardiovascular Imaging, Ospedale Medico-Chirurgico Accreditato Villa dei Fiori, 80011 Acerra, Italy

Abstract

Cardiac magnetic resonance (CMR) imaging has witnessed substantial progress with the advent of parametric mapping techniques, most notably T1 and T2 mapping. These advanced techniques provide valuable insights into a wide range of cardiac conditions, including ischemic heart disease, cardiomyopathies, inflammatory cardiomyopathies, heart valve disease, and athlete’s heart. Mapping could be the first sign of myocardial injury and oftentimes precedes symptoms, changes in ejection fraction, and irreversible myocardial remodeling. The ability of parametric mapping to offer a quantitative assessment of myocardial tissue properties addresses the limitations of conventional CMR methods, which often rely on qualitative or semiquantitative data. However, challenges persist, especially in terms of standardization and reference value establishment, hindering the wider clinical adoption of parametric mapping. Future developments should prioritize the standardization of techniques to enhance their clinical applicability, ultimately optimizing patient care pathways and outcomes. In this review, we endeavor to provide insights into the potential contributions of CMR mapping techniques in enhancing the diagnostic processes across a range of cardiac conditions.

Publisher

MDPI AG

Subject

General Medicine

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