Emergence in Complex Physiological Processes: The Case of Vitamin B12 Functions in Erythropoiesis

Author:

Bellazzi Francesca1ORCID,Bertolaso Marta2

Affiliation:

1. Department of Philosophy, University of Birmingham, Birmingham B15 2TT, UK

2. Research Unit of Philosophy of Science and Human Development, Department of Science and Technology for Sustainable Development and One Health, Campus BioMedico, 00128 Rome, Italy

Abstract

In this paper, we will explore the relation between molecular structure and functions displayed by biochemical molecules in complex physiological processes by using tools from the philosophy of science and the philosophy of scientific practice. We will argue that biochemical functions are weakly emergent from molecular structure by using an account of weak. In order to explore this thesis, we will consider the role of vitamin B12 in contributing to the process of erythropoiesis. The structure of the paper is the following: First, we will consider biochemical functions and why they cannot be easily reduced to their chemical realisers. We will suggest weak emergence as an alternative while also accounting for the relevance of the context, in our case, systemic and organisational. The paper will conclude by considering (1) how the usage of tools from the philosophy of science, such as weak emergence, can aid our understanding of the relations between the components of complex phenomena, such as erythropoiesis, and (2) how the philosophy of scientific practice sheds light on the explanatory role of processes that are dynamically stabilised and the different levels of organisation implied.

Publisher

MDPI AG

Reference26 articles.

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3. Tahko, T.E. (2020). Where do you get your protein? Or: Biochemical realization. Br. J. Philos. Sci., 71.

4. Bellazzi, F. (Br. J. Philos. Sci., 2022). Biochemical functions, Br. J. Philos. Sci., forthcoming.

5. Emergence without limits: The case of phonons;Franklin;Stud. Hist. Philos. Sci. Part B Stud. Hist. Philos. Mod. Phys.,2018

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