Serological Evidence of Zika Virus Infections in Sudan-Reference-Cited by-同舟云学术

Serological Evidence of Zika Virus Infections in Sudan

Published:2024-06-28 Issue:7 Volume:16 Page:1045
ISSN:1999-4915
Container-title:Viruses
language:en
Short-container-title:Viruses

Author:

Adam Awadalkareem¹,Wenzel Robert¹^ORCID,Unger Elisabeth¹^ORCID,Reiche Sven²^ORCID,Jassoy Christian¹

Affiliation:

1. Institute for Medical Microbiology and Virology, Faculty of Medicine, University of Leipzig Medical Center, University of Leipzig, 04103 Leipzig, Germany

2. Department of Experimental Animal Facilities and Biorisk Management, Friedrich-Loeffler-Institut, 17493 Greifswald-Insel Riems, Germany

Abstract

Little is known about the frequency of Zika virus (ZIKV) infections in Sudan. The aim of this study was to obtain data on the prevalence of ZIKV infections and the immunity of the population in the country. To this end, 198 sera obtained between December 2012 and January 2013 in different regions in Sudan were examined for neutralizing antibodies against ZIKV, dengue virus (DENV), and yellow fever virus (YFV). The sera were non-randomly selected. The neutralization titers were compared with each other and with the WHO 1st International Standard for anti-Asian lineage Zika virus antibody. Twenty-six sera neutralized ZIKV. One-third of these sera had higher neutralization titers against ZIKV than against DENV-2 and -3. Two sera showed higher neutralization titers than the WHO standard for ZIKV antibodies. These data suggest occasional ZIKV infections in Sudan. The low percentage of sera in this cohort that neutralized ZIKV indicates that, in the study period, the population was susceptible to ZIKV infection.

Publisher

MDPI AG

Link

https://www.mdpi.com/1999-4915/16/7/1045/pdf

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