The Use of Repetitive Transcranial Magnetic Stimulations for the Treatment of Post-Traumatic Stress Disorder: A Scoping Review

Abstract

Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive procedure in which brain neural activity is stimulated by the direct application of a magnetic field to the scalp. Despite its wide and continuous usage for the management of psychiatric disorders, the use of rTMS for post-traumatic stress disorder (PTSD) is not well established and evaluated by researchers. This scoping review seeks to explore the relevant literature available regarding the use of rTMS as a mode of treatment for PTSD, to map evidence in support of the use of rTMS for PTSD, and recommendations on future clinical and research work. Five databases were searched (MEDLINE, CINAHL, Psych INFO, SCOPUS, and EMBASE) to identify empirical studies and randomized controlled trials aimed at the treatment of PTSD with rTMS. A total of 10 studies were eligible for this review. The search results are up to date as of the date of the electronic data search of 20 December 2020. The frequencies applied in the studies ranged from low (1 Hz) to high (10 Hz) at different thresholds. Nine reported significant positive outcomes and PTSD symptoms improvement. rTMS was reported as well tolerated with no significant side effects. The application of rTMS for PTSD looks promising despite the diversity in terms of its outcomes and its clinical significance. Studies with well-defined stimulation parameters need to be conducted in the future.