Dietary Intervention during Weaning and Development of Food Allergy: What Is the State of the Art?

Author:

Gravina Alessandro1,Olivero Francesca2,Brindisi Giulia1ORCID,Comerci Antonia Fortunata1,Ranucci Chiara1,Fiorentini Cinzia1ORCID,Sculco Eleonora3,Figliozzi Ethel1,Tudini Laura1,Matys Viviana1ORCID,De Canditiis Daniela4ORCID,Piccioni Maria Grazia1,Zicari Anna Maria1,Anania Caterina1

Affiliation:

1. Department of Maternal Infantile and Urological Science, Sapienza University of Rome, 00161 Rome, Italy

2. Independent Researcher, 00161 Rome, Italy

3. Department of Translation and Precision Medicine, Sapienza University of Rome, 00161 Rome, Italy

4. Institute of Applied Calculus-CNR Rome, 00185 Rome, Italy

Abstract

Food allergy (FA) affects approximately 6–8% of children worldwide causing a significant impact on the quality of life of children and their families. In past years, the possible role of weaning in the development of FA has been studied. According to recent studies, this is still controversial and influenced by several factors, such as the type of food, the age at food introduction and family history. In this narrative review, we aimed to collect the most recent evidence about weaning and its role in FA development, organizing the gathered data based on both the type of study and the food. As shown in most of the studies included in this review, early food introduction did not show a potential protective role against FA development, and we conclude that further evidence is needed from future clinical trials.

Publisher

MDPI AG

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