How Does Radiation Affect Curcumin Raw Material?

Author:

Rosiak Natalia1ORCID,Garbiec Ewa1ORCID,Bednarski Waldemar2ORCID,Skibiński Robert3ORCID,Lewandowska Kornelia2ORCID,Bazan-Woźniak Aleksandra4ORCID,Pietrzak Robert4ORCID,Cielecka-Piontek Judyta1ORCID,Zalewski Przemysław1ORCID

Affiliation:

1. Department of Pharmacognosy and Biomaterials, Poznan University of Medical Sciences, Rokietnicka 3, 60-806 Poznan, Poland

2. Institute of Molecular Physics, Polish Academy of Sciences, Smoluchowskiego 17, 60-179 Poznan, Poland

3. Department of Medicinal Chemistry, Medical University of Lublin, Jaczewskiego 4, 20-090 Lublin, Poland

4. Faculty of Chemistry, Adam Mickiewicz University in Poznan, Uniwersytetu Poznańskiego 8, 61-614 Poznan, Poland

Abstract

Turmeric, known for its curcuminoid-rich rhizome, particularly curcumin, exhibits notable antioxidant and antiviral properties. The likelihood of microbial contamination necessitates finding reliable techniques for subjecting the sample to radiation from this plant-based raw material. One alternative is to expose curcumin to radiation (e-beam), which was carried out as part of this research. Confirmation of the lack of curcumin decomposition was carried out using HPLC-DAD/MS techniques. Additionally, using the EPR technique, the generated free radicals were defined as radiation effects. Using a number of methods to assess the ability to scavenge free radicals (DPPH, ABTS, CUPRAC, and FRAP), a slight decrease in the activity of curcumin raw material was determined. The analysis of the characteristic bands in the FT-IR spectra allowed us to indicate changes in the phenolic OH groups as an effect of the presence of radicals formed.

Funder

Polish National Agency for Academic Exchange

Publisher

MDPI AG

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