CardioRVAR: A New R Package and Shiny Application for the Evaluation of Closed-Loop Cardiovascular Interactions-Reference-Cited by-同舟云学术

CardioRVAR: A New R Package and Shiny Application for the Evaluation of Closed-Loop Cardiovascular Interactions

Published:2023-11-16 Issue:11 Volume:12 Page:1438
ISSN:2079-7737
Container-title:Biology
language:en
Short-container-title:Biology

Author:

Chao-Écija Alvaro¹^ORCID,López-González Manuel Víctor¹²^ORCID,Dawid-Milner Marc Stefan¹²^ORCID

Affiliation:

1. Autonomic Nervous System Unit, CIMES, School of Medicine, University of Málaga, 29071 Malaga, Spain

2. Biomedical Research Institute of Málaga (IBIMA), 29590 Malaga, Spain

Abstract

CardioRVAR is a new R package designed for the complete evaluation of closed-loop cardiovascular interactions and baroreflex sensitivity estimated from continuous non-invasive heart rate and blood pressure recordings. In this work, we highlight the importance of this software tool in the context of human cardiovascular and autonomic neurophysiology. A summary of the main algorithms that CardioRVAR uses are reviewed, and the workflow of this package is also discussed. We present the results obtained from this tool after its application in three clinical settings. These results support the potential clinical and scientific applications of this tool. The open-source tool can be downloaded from a public GitHub repository, as well as its specific Shiny application, CardioRVARapp. The open-source nature of the tool may benefit the future continuation of this work.

Funder

Junta de Andalucía, Group

University of Málaga

Publisher

MDPI AG

Subject

General Agricultural and Biological Sciences,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology

Link

https://www.mdpi.com/2079-7737/12/11/1438/pdf

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