Looking Back, Going Forward: Understanding Cardiac Pathophysiology from Pressure–Volume Loops

Author:

Protti Ilaria12,van den Enden Antoon1ORCID,Van Mieghem Nicolas M.1,Meuwese Christiaan L.1,Meani Paolo345

Affiliation:

1. Department of Intensive Care and Cardiology, Cardiovascular Institute, Thoraxcenter, Erasmus University Medical Center, 3012 Rotterdam, The Netherlands

2. Department of Pathophysiology and Transplantation, Università degli Studi di Milano, 20122 Milan, Italy

3. Department of Cardiothoracic Surgery, Heart and Vascular Centre, Maastricht University Medical Centre, 6229 Maastricht, The Netherlands

4. Faculty of Health, Medicine and Life Sciences, Maastricht University, 6211 Maastricht, The Netherlands

5. Thoracic Research Center, Innovative Medical Forum, Collegium Medicum Nicolaus Copernicus University, 85-094 Bydgoszcz, Poland

Abstract

Knowing cardiac physiology is essential for health care professionals working in the cardiovascular field. Pressure–volume loops (PVLs) offer a unique understanding of the myocardial working and have become pivotal in complex pathophysiological scenarios, such as profound cardiogenic shock or when mechanical circulatory supports are implemented. This review provides a comprehensive summary of the left and right ventricle physiology, based on the PVL interpretation.

Publisher

MDPI AG

Subject

General Agricultural and Biological Sciences,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology

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