Affiliation:
1. R&D Department, Complife Italia Srl, 27028 San Martino Siccomario, Italy
2. Clinical Testing Department, Complife Italia Srl, 27028 San Martino Siccomario, Italy
Abstract
Atopic dermatitis (AD) is a chronic inflammatory and pruritic skin disease with a worldwide progressive increase in its incidence. In this clinical study, we studied the effect of a cosmetic treatment composed of a cleanser, and a body and face cream, on subjects (babies, children, and adults) suffering from mild-to-moderate AD. The product effect on AD clinical signs was investigated by SCORing Atopic Dermatitis (SCORAD) index, subjective evaluation, skin erythema index, and transepidermal water loss (TEWL) measurements. The products were shown to be effective in improving the AD scoring by SCORAD in all the groups, and a trend towards the decrease of the erythema index and the TEWL in the adult population. An improvement in itching sensation, skin redness, and skin dryness scoring was also reported by the subjects. Results from this study demonstrate the efficacy of the tested products in decreasing the overall AD severity through 28 days of treatment. Overall, the first results occurred within 14 days of treatment.
Subject
Dermatology,Pharmaceutical Science,Aging,Chemical Engineering (miscellaneous),Surgery
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