Abstract
The design of a fractional-order closed-loop model reference adaptive control (FOCMRAC) for anesthesia based on a fractional-order model (FOM) is proposed in the paper. This proposed model gets around many difficulties, namely, unknown parameters, lack of state measurement, inter and intra-patient variability, and variable time-delay, encountered in controller designs based on the PK/PD model commonly used for control of anesthesia, and allows to design a simple adaptive controller based on the Lyapunov analysis. Simulations illustrate the effectiveness and robustness of the proposed control.
Funder
Consejo Nacional de Ciencia y Tecnología
Subject
Computational Mathematics,Computational Theory and Mathematics,Numerical Analysis,Theoretical Computer Science
Cited by
9 articles.
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